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Melanoma Evidence-based Series (EBS) and Practice Guidelines (PG)

Melanoma includes cancers of the skin.

The Melanoma Disease Site Group (Melanoma DSG) produces evidence-based reports to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances.  The titles of the reports produced to date by the DSG are listed below, with links to the PDF versions of those reports.   

The PEBC has a formal and standardized process to ensure the currency of each document. This process guides clinical experts to assess a document’s current status and relevance (please see the PEBC Assessment & Review Protocol for more information). A final status statement is added to the document when this review process is complete. The current status of each guidance document is noted beside the title and link as outlined below:

  • Documents listed as CURRENT are 3 years old or less, up-to-date, and can be used for decision making.
  • Documents listed as IN REVIEW are undergoing assessment for currency and relevance.  The DSG/GDG has determined that it is still appropriate for this document to continue to be available while this updating process unfolds.
  • Documents that are listed as “FOR EDUCATION AND INFORMATION PURPOSES” are documents for which no further updates are planned and whose recommendations may no longer be consistent with recent evidence.  They may be of educational, historical, clinical, or system interest.

If you have any questions regarding a document that is “In Review,” please contact the PEBC ( or the lead author of the document. 

  • Follow-up of Patients with Cutaneous Melanoma who were Treated with Curative Intent
    Guideline 8-7: November 2015
    Status: CURRENT
  • The Use of Adjuvant Radiation Therapy for Curatively Resected Cutaneous Melanoma
    Guideline 8-9: January 2016
    Status: CURRENT
  • The Use of Indoor Tanning Devices and the Risk of Developing Cutaneous Malignant Melanoma: A Systematic Review and Clinical Practice Guideline
    8-8  EBS: August 2014
    Status: CURRENT
  • Surgical Management of Patients with Lymph Node Metastases from Cutaneous Melanoma of the Trunk or Extremities
    8-6 Version 2 EBS: October 2016 
    Status: CURRENT
  • Primary Excision Margins and Sentinel Lymph Node Biopsy in Clinically Node-Negative Cutaneous Melanoma of the Trunk or Extremities
    8-2 EBS: May 17, 2010
    Status: IN REVIEW
  • Systemic Adjuvant Therapy for Patients at High Risk for Recurrent Melanoma
    8-1 EBS Version 4: November 2013
    Status: IN REVIEW

For Education and Information Purposes

  • Single-Agent Interleukin-2 in the Treatment of Metastatic Malignant Melanoma
  • Biochemotherapy for the Treatment of Metastatic Malignant Melanoma
  • Temozolomide for the Treatment of Metastatic Melanoma
Program in Evidence-Based Care (PEBC)
McMaster University, Juravinski Site
G Wing, 2nd Floor
711 Concession Street
Hamilton, Ontario, Canada
L8V 1C3

Phone: 905.527.4322 ext. 42822
Fax: 905.526.6775
Last modified: Fri, Jul 28, 2017
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