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Pathology and Laboratory Medicine Evidence-based Series (EBS)

The Pathology and Laboratory Medicine Evidence-Based Series are produced by Expert Panels convened by Cancer Care Ontario that work together with the PEBC to gather and examine evidence on specific topics related to providing high quality pathology and laboratory medicine services for people affected by cancer in Ontario.

The PEBC has a formal and standardized process to ensure the currency of each document (please see the PEBC Assessment & Review Protocol for more information). This process guides clinical experts to assess a document’s current status and relevance. A final status statement is added to the document when this review process is complete. The current status of each guidance document is noted beside the title and link as outlined below:

  • Documents listed as CURRENT are 3 years old or less, up-to-date, and can be used for decision making.
  • Documents listed as IN REVIEW are undergoing assessment for currency and relevance.  The DSG/GDG has determined that it is still appropriate for this document to continue to be available while this updating process unfolds.
  • Documents that are listed as “FOR EDUCATION AND INFORMATION PURPOSES” are documents for which no further updates are planned and whose recommendations may no longer be consistent with recent evidence.  They may be of educational, historical, clinical, or system interest.

If you have any questions regarding a document that is “In Review,” please contact the PEBC ( or the lead author of the document.

Evidence Summaries

Best Practices for Oncologic Pathology Secondary Review:

  • Methods and Overview
    Evidence Summary 22-2M: June 2014
  • Breast Cancer
    Evidence Summary 22-2-1: June 2014
  • Gastrointestinal Cancers
    Evidence Summary 22-2-2: June 2014
  • Genitourinary Cancers
    Evidence Summary 22-2-3: June 2014
  • Gynecologic Cancers
    Evidence Summary 22-2-4: June 2014
  • Head and Neck Cancer
    Evidence Summary 22-2-5: June 2014
  • Hematologic Cancer
    Evidence Summary 22-2-6: June 2014
  • Lung Cancer
    Evidence Summary 22-2-7: June 2014
  • Cutaneous Melanoma and Other Skin Cancers
    Evidence Summary 22-2-8: June 2014
  • Central Nervous System (CNS) Tumours
    Evidence Summary 22-2-9: June 2014
  • Bone and Soft Tissue Cancers (Sarcoma)
    Evidence Summary 22-2-10: June 2014

For Education and Information Purposes

  • Guideline on Hormone Receptor Testing in Breast Cancer
Last modified: Tue, May 30, 2017
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